Endocrine Abstracts

Abstract: Radioiodine is a definite treatment option for toxic goiter. We have evaluated volume reduction, function and autoimmunity outcomes with a 15 mCi fixed regimen. Patients with at least one US evaluation before and after Iodine-131 therapy and with at least one year of follow-up were included. TSH, free-T4, antibodies and goiter volume before and yearly after Iodine-131 treatment were analysed for the length of the entire follow-up. The total 151 patients, 72.6% female...

Background: Acromegaly is associated with increased risk of coronary atherosclerosis and cardiovascular mortality. Changes in coagulation and fibrinolysis markers in acromegalic patients have been shown to indicate increase in the risk of developing cardiovascular disease. Mean platelet volume (MPV) is a marker of platelet functions and activity, and increased MPV is an independent risk factor of myocardial infarction and thrombotic events. In this study, we examined the level...

Introduction: Mean platelet volume (MPV) which is part of a complete blood count measures the platelet size. There are many studies in the literature that it is an indicator of platelet function in thrombotic and inflammatory diseases. However, the number of studies about changes in MPV after treatment in thyroid disease is very limited. In this study, we aimed to reveal the MPV change with treatment in patients with hypothyroidism and hyperthyroidism.Ma...

Background and aims: Intermediate hyperglycemia has been established to increase cardiovascular disease (CVD) risk. The increased platelet activity is believed to play a central role in pathogenesis of CVD. Mean platelet volume (MPV) and urinary 11-dehydro-thromboxane B2 (11-dehydro-TxB2) level have been validated as a reliable and non-invasive marker for platelet activity. The objective was to evaluate the association between these markers and CVD risk b...

Background: Measuring testicular volume (TV) by orchidometer is a standard method of male pubertal staging. Previously we have developed a simulation model for TV estimation with different sized silicon testes housed in latex scrotum and displayed on paediatric mannequins. When used in a study of 215 paediatric endocrinologists TV was measured accurately on only 33% of occasions. Intra-observer reliability was also lacking with participants giving different estimations for the...

Introduction: The disorders of orgasm/ejaculation include premature ejaculation, delayed ejaculation and perceived ejaculate volume reduction (PEVR). To explore the specific associations of PEVR in subjects with erectile dysfunction (ED).Methods: A consecutive series of 3141 subjects (mean age 51.6±13.1 years old) was studied. Among these, 71 have been excluded because they underwent prostate surgery. Different clinical and biochemical factors were ...

Background: Epidemiologocal data suggest an continuous increase in thyroid carcinoma diagnosis. Therefore, thyroidectomy rates are projected to increase world-wide in exponential scale. In Switzerland, the institutional number of thyroidectomies varies, however there is no data yet on the association between institutional thyroidectomy volume and clinical outcome.Methods: Cross-sectional analysis of adult inpatients in Swiss hospitals using a nation-wide...

Introduction: Studies investigating the association between serum IGF-1, and thyroid nodule, ovarian or thyroid volume in polycystic ovarian syndrome (PCOS) are limited. We aimed to analyze the association between serum IGF-1 level, and ovarian or thyroid volume, or thyroid nodule in PCOS.Materials and methods: The study was performed between June 2017 and August 2019 as prospective design. The patients referred to our medical faculty were included. Adul...

Introduction and aims: Subacute thyroiditis (ST) is a spontaneous remitting inflammatory disease of thyroid gland. Although there is no clear evidence for its specific etiology, multiple factors may responsible for this inflammatory reaction. Mean platelet volume (MPV) is a new important inflammatory marker that indicates disease activity. Aim of this study is to evaluate MPV value in patients with subacute thyroiditis.Materials and methods: Thirty-one p...

Objective: The role of smoking in the pathogenesis of thyroid enlargement is currently under debate. The aim of this paper was to investigate the role of smoking on thyroid volume change and incident goiter for different age-strata in a region with normalized iodine supply.Methods: The population-based Study of Health in Pomerania (SHIP) compromised 3300 subjects with complete 5-year examination follow-up. Data from 2484 participants without known thyroi...